Introduction to CAS 62-53-3 Aniline

Aniline, with CAS number 62-53-3, also known as aminobenzene or aniline oil, is the simplest primary aromatic amine. Its chemical formula is C₆H₅NH₂ (C₆H₇N) and its molecular weight is 93.13. It is one of the most important basic intermediates in the organic chemical industry, widely used in various industrial fields. At the same time, it has obvious toxicity and strict safety protection measures are required.

Aniline has distinct physical and chemical properties: it is a colorless to pale yellow oily liquid at room temperature, with a special aromatic amine odor. Its color will gradually darken under the action of light and air, and it will solidify when the temperature is lower than 21°F (about -6.1℃). It is slightly soluble in water with a solubility of about 4%, miscible with many organic solvents such as ethanol, ether and benzene, and can volatilize with water vapor. It has weak alkalinity and can react with acids to form salts. It is chemically active, prone to substitution reactions such as oxidation, diazotization and alkylation, and can polymerize to form polyaniline under acidic conditions. Its key physical parameters are: relative density 1.02, boiling point 184.1℃, flash point 76℃, explosive limit 1.3%~11.0%. It is a flammable liquid and should be kept away from fire and heat sources.

In the field of application, aniline is an indispensable chemical raw material. In the dye industry, it is the core intermediate for the production of various dyes and pigments such as Acid Ink Blue G, Acid Light Yellow and Aniline Black. In the pesticide field, it can be used to synthesize insecticides and fungicides such as dichlorvos and nitrofen. In the pharmaceutical field, it is an important raw material for the synthesis of antipyretic and analgesic drugs such as paracetamol and acetanilide. In addition, it is widely used in the manufacture of rubber additives, antioxidants, plastics, varnishes, films, as well as explosive stabilizers, gasoline anti-explosives and solvents. It can also be used in the production of MDI (diphenylmethane diisocyanate) in the polyurethane industry.

Safety protection is the focus in the use of aniline. Aniline is highly toxic and can invade the human body through various ways such as respiratory tract, skin absorption, ingestion, and skin and eye contact. Short-term massive contact can cause symptoms such as headache, dizziness, cyanosis and dyspnea. Long-term contact may damage organs such as blood, liver and kidneys. It is classified as a Class 3 carcinogen by the World Health Organization (limited evidence of carcinogenicity to humans). During operation, full-face gas masks, rubber impermeable overalls and oil-resistant gloves should be worn. Smoking, eating and drinking are strictly prohibited in the workplace, and contact with oxidants, strong acids and other substances should be avoided. In case of leakage, the contaminated area should be isolated in time, treated with sand adsorption or a large amount of water flushing. In case of contact, corresponding first aid measures should be taken immediately and medical treatment should be sought.